منابع مشابه
Ancestral Reconstruction
Ancestral reconstruction is the extrapolation back in time from measured characteristics of individuals (or populations) to their common ancestors. It is an important application of phylogenetics, the reconstruction and study of the evolutionary relationships among individuals, populations, or species to their ancestors. In the context of biology, ancestral reconstruction can be used to recover...
متن کاملReconstruction of Ancestral Protosplice Sites
Most of the eukaryotic protein-coding genes are interrupted by multiple introns. A substantial fraction of introns occupy the same position in orthologous genes from distant eukaryotes, such as plants and animals, and consequently are inferred to have been inherited from the common ancestor of these organisms. In contrast to these conserved introns, many other introns appear to have been gained...
متن کاملReconstruction of Ancestral Metabolic Enzymes Reveals Molecular Mechanisms Underlying Evolutionary Innovation through Gene Duplication
Gene duplications are believed to facilitate evolutionary innovation. However, the mechanisms shaping the fate of duplicated genes remain heavily debated because the molecular processes and evolutionary forces involved are difficult to reconstruct. Here, we study a large family of fungal glucosidase genes that underwent several duplication events. We reconstruct all key ancestral enzymes and sh...
متن کاملAncestral sequence reconstruction with phangorn
For parsimony analysis of the edge length represent the observed number of changes. Reconstructiong ancestral states therefore defines also the edge lengths of a tree. However there can exist several equally parsimonious reconstructions or states can be ambiguous and therefore edge length can differ. ”MPR” reconstructs the ancestral states for each (internal) node as if the tree would be rooted...
متن کاملAncestral Reconstruction for Association Mapping
One of the greatest promises of modern genetics is the ability to identify loci responsible for, or at least highly correlated with, important physical traits and disease susceptibility. This will enable benefits ranging from improved disease risk assessment and crop design to ultimately a better understanding of how genotype variation effects variations in phenotypes. A key component in this t...
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ژورنال
عنوان ژورنال: Perspectives in Science
سال: 2016
ISSN: 2213-0209
DOI: 10.1016/j.pisc.2016.08.002